DICTIONARY
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- Epitope: A specific portion of an antigen that is recognized and bound by an antibody or TCR-MHC combination, which is also called an antigenic determinant--determining piece that binds to an immunogen.
- Plasmacytomas: are tumors of plasma cells, the end-stage cell of B cell differentiation, and the cells from that tumor are typically located in the bone marrow.
- Once the tumor metastasizes into multiple bone marrow, the tumor is referred to as multiple myelomas, which secretes large amounts of monoclonal antibodies into the serum and fluids of the patients.
Little Knowledge
B cells secrete antibodies or immunoglobulins. These antibodies are IgA, IgE, IgG, IgD, and IgM. These subclasses have different structures composed of heavy chains and light chains. There are more kappa light chains than there is a lambda. Only IgA & IgM are comprised of J chain; contain a different number of Ig domains.
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Works cited
- Fyeahmedlab. "Diary of a Medical Scientist." Diary of a Medical Scientist. N.p., n.d. Web. 13 Oct. 2016. <http://fyeahmedlab.tumblr.com/post/42418326885>.
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